Table 3.
Summary of the experimental studies related to the harmful and beneficial effects of ADSCs on hepatocellular carcinoma cell lines.
| Effect | Method | Cell Line | Ref. |
|---|---|---|---|
| Inhibition of proliferation | Co-culture with ADSCs | HepG2 | [84,85] |
| PLC-PRF-5 | [84] | ||
| Culture with ADSC-derived conditioned medium | HepG2 | [83,84,118] | |
| Huh7 | [83] | ||
| SMMC7721 | [83] | ||
| Bel7402 | [83] | ||
| Induction of apoptosis | Co-culture with ADSCs | HepG2 | [84,85] |
| PLC-PRF-5 | [84] | ||
| Culture with ADSC-derived | SMMC7721 | [83] | |
| conditioned medium | HepG2 | [84,118] | |
| PLC-PRF-5 | [84] | ||
| Inhibition of migration | Co-culture with ADSCs | HepG2 | [84,85] |
| PLC-PRF-5 | [84] | ||
| Culture with ADSC-derived conditioned medium | HepG2 | [84,118] | |
| Reduction of invasiveness | Co-culture with ADSCs | HepG2 | [84] |
| Culture with ADSC-derived conditioned medium | HepG2 | [84,85,118] | |
| Promotion of proliferation and migration | Culture with ADSC-derived conditioned medium | AZACH | [119] |