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High-fat diet feeding is associated with overactivation of proinflammatory cytokine expression in guinea pigs. Column graphs represent ELISA assay quantification (in pg/mL), of IL-6 (A,B), IL-1β (C,D), TNF-α (E,F) measured in LFD and HFD guinea pig serum and ventricular samples, respectively. Comparison is made between serum vs. cardiac levels for a specific cytokine. Data columns are mean ± S.E.M, n = 4–7 LFD, 9–14 HFD. * Statistical significance at p < 0.05.
