Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jul 21;25(14):7976. doi: 10.3390/ijms25147976

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Immune response of chickens and rabbits following immunization with three different SARS-CoV-2 antigen preparations, the RBD antigen (SARS-CoV-2 receptor-binding-domain coupled to LS-particles), the S1 antigen (S1 subunit of the SARS-CoV-2 spike protein coupled to LS-particles) and an inactivated SARS-CoV-2 full-virus preparation. (A) The immunization and sampling scheme for the different antigens. (B) All sera (dilution factor 1:100) from immunized chickens and reference rabbits were tested by RBD-specific ELISA, and samples from animals immunized with the full-virus preparation were also tested with N-specific ELISA. The mean with SEM of individual animals is depicted for the sera. (C) Yolk samples of the chicken were analyzed by RBD-specific ELISA and for the whole-virus group with the N-specific ELISA, in addition. The single values for the weekly yolk-pool samples are shown.