Table 1.
log2 VNT100 titer | ||||||||
virus used in neutralization assay | ||||||||
antigen | species | biological replicate | WT | Alpha | Beta | Delta | BA.1 | BA.5 |
RBD | #1 | 11.3 | 12 | 10.3 | 12.3 | 9.7 | 8.7 | |
#2 | 10.7 | 11.7 | 9 | 10.3 | 4 | 4 | ||
#3 | 9.7 | 12 | 10.3 | 10.7 | 8 | 4 | ||
yolk pool | 7 | 11.3 | 8.3 | 9 | 7.3 | 5.7 | ||
#1 | 11.7 | 11.3 | 11.7 | 10.7 | 12 | 7.3 | ||
#2 | 10.7 | 10.3 | 10.7 | 9 | 10.7 | 7.3 | ||
S1 | #1 | 4 | 4 | 4 | 4 | 4 | 4 | |
#2 | 4 | 4 | 4 | 4 | 4 | 4 | ||
#3 | 7 | 8.7 | 4 | 5.7 | 4 | 4 | ||
yolk pool | 4 | 4.7 | 4 | 4 | 4 | 4 | ||
#1 | 4 | 4 | 4 | 4 | 4 | 4 | ||
#2 | 5.3 | 5 | 5.3 | 4 | 5.7 | 4 | ||
whole virus | #1 | 9 | 6.3 | 8.3 | 6.3 | 7 | 5 | |
#2 | 8.7 | 5 | 9.7 | 5 | 8 | 5 | ||
#3 | 9 | 8.7 | 8.7 | 8.7 | 9 | 7.7 | ||
yolk pool | 6 | 9 | 7 | 8 | 6 | 6 | ||
Log2 VNT titer of ≤4 = negative/below tested threshold | ||||||||
Log2 VNT titer of >4 and ≤7 = positive at a moderate level | ||||||||
Log2 VNT titer of >7 and ≤10 = positive at a high level | ||||||||
Log2 VNT titer of >10 = positive at a very high level |