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. 2024 Jul 5;3(8):101088. doi: 10.1016/j.jacadv.2024.101088

Table 3.

Association Between Adverse Pregnancy Outcome History and Invasive Revascularization Procedure Among Women Presenting With First Time Myocardial Infarction (N = 8,320)

Model I
Model II
OR (95% CI) P Value OR (95% CI) P Value
Preterm delivery (n revascularization/n MI)
 Never preterm delivery (2,344/7,019) 1.00 (reference) 1.00 (reference)
 Ever preterm delivery (436/1,301) 1.01 (0.89-1.15) 0.82 1.01 (0.89-1.15) 0.91
 Late preterm delivery (286/863) 0.99 (0.86-1.16) 0.95 0.99 (0.85-1.15) 0.88
 Very preterm delivery (150/438) 1.05 (0.86-1.29) 0.61 1.05 (0.85-1.29) 0.66
Small for gestational age infant (n revascularization/n MI)
 Never small for gestational age infant (2,436/7,433) 1.00 (reference) 1.00 (reference)
 Ever small for gestational age infant (344/887) 1.30 (1.12-1.50) <0.001 1.20 (1.04-1.39) 0.01
Hypertensive disorder of pregnancy (n revascularization/n MI)
 Normotensive (2,441/7,242) 1.00 (reference) 1.00 (reference)
 Hypertensive disorder of pregnancy (339/1,078) 0.91 (0.79-1.05) 0.19 1.03 (0.89-1.19) 0.69
 Preterm preeclampsia (77/206) 1.21 (0.90-1.61) 0.20 1.43 (1.07-1.92) 0.02
 Term preeclampsia (149/518) 0.80 (0.66-0.98) 0.03 0.89 (0.73-1.09) 0.27
 Non-preeclampsia hypertension (113/354) 0.92 (0.73-1.16) 0.50 1.04 (0.82-1.31) 0.76

Results from logistic regression multiple imputation analysis.

Preterm delivery is defined as a woman’s most preterm delivery prior to her first MI. Hypertensive disorders of pregnancy are defined as a woman’s most serious diagnosis prior to her first MI.

Model I includes adverse pregnancy outcome history; age at first time MI [continuous].

Model II additionally includes diabetes [yes/no]; hypertension [yes/no]; treatment for dyslipidemia [yes/no]; smoking status [never smoker, current smoker, ex-smoker >1 month]; BMI [continuous].

BMI = body mass index; MI = myocardial infarction.