TME	Tumor microenvironment
cGAS	cyclic GMP–AMP synthase
STING	stimulator of interferon genes
DAMP	damage-associated molecular pattern
dsDNA	double-stranded DNA
cGAMP	cyclic GMP-AMP
ATP	Adenosine Triphosphate
CTD	C-terminal nucleotide transferase domain
ER	Endoplasmic reticulum
CTT	C-terminal tail
ERGIC	endoplasmic reticulum Golgi intermediate chamber
TBK1	tank-binding kinase 1
IKK	inhibitor of kappa B kinas
IRF3	interferon regulatory factor 3
IFN	interferon
NF-kB	nuclear factor kappa B
TAK1	TGF-beta-activated kinase 1
IKK	I kappa B kinase
NK	cells natural killer cells
CRC	colorectal cancer
CDN	cyclic dinucleotides
NCDN	non- cyclic dinucleotides
OS	overall survival
HER2	human epidermalal growth factor receptor receptor 2
PD-1	programmed death-1
PD-L1	Programmed cell death ligand 1
MFC	mouse forestomach carcinoma