Table 1.
Results of the seven positive A. fumigatus isolates for the surveyor nuclease technique, cyp51A gene sequencing, and Minimum Inhibitory Concentration for the azoles Itraconazole, Voriconazole, and Posaconazole.
| Strain | Date | Patient | Clinical Material | Surveyor Nuclease | cyp51A Gene | MIC (µg/mL) | ||
|---|---|---|---|---|---|---|---|---|
| VRC | ITC | POS | ||||||
| LIF 3061 | 27 September 2017 | 7 | Sputum | + | F46Y, M172V, N248T, D255E and K427E | 2 | 1 | 0.5 |
| LIF 2509 | 20 October 2015 | 30 | Sputum | + | N248K | 0.5 | 0.5 | 0.5 |
| LIF 2543 | 17 November 2015 | 31 | Sputum | + | N248K | 0.5 | 0.25 | 0.25 |
| LIF 3105 | 9 January 2018 | 31 | Sputum | + | N248K | 0.5 | 0.5 | 0.5 |
| LIF 3261 | 21 August 2018 | 31 | Sputum | + | N248K | 1 | 1 | 0.5 |
| LIF 3318 | 17 December 2018 | 31 | Sputum | + | N248K | 1 | 0.5 | 0.25 |
| LIF 3302 | 28 September 2018 | 41 | Sputum | + | F46Y, M172V, N248T, D255E, and K427E | 1 | 1 | 0.5 |
+ Positive for surveyor nuclease assay. VRC: Voriconazole; ITC: Itraconazole; POS: Posaconazole.