Figure 2.

Schematic illustration of antioxidant delivery system for the treatment of diabetic wound healing. (a) Schematic representations of CNPs@GMs/hydrogel and the process of drug release at the wound bed in diabetic mice. (b) Representative images of wounds in diabetic mice for 0-20 days. (c) Dermal wound area (%), skin thickness, and epidermal thickness in the different groups. Reprinted with permission from Liu et al. [86] Copyright 2018, American Chemical Society. (d) Ce@LTA-NPs-F127/CS hydrogel was designed as a multi-target combination therapy for diabetic wound healing. (e) Traces of the wound closure during 14 days. Reprinted with permission from Qi et al. [77] Copyright 2021, Springer Nature.