Figure 4.

Schematic illustration of antioxidant delivery system for the treatment of organ dysfunction. (a) Schematic illustration of Cu_5.4O ultra-small nanoparticles in the treatment of ROS-related diseases. Reprinted with permission from Liu et al. [105] Copyright 2020, Nature Publishing Group. (b) Schematic illustration of Fe-Cur NP synthesis and Fe-Cur NP based treatment for ALI in mice and fluorescence images of ROS stained lung slices. Reprinted with permission from Yuan et al. [106] Copyright 2021, American Chemical Society. (c) Schematic for the preparation of Ce-ReV. TEM images of Ce-ReV stained with uranyl acetate and high-resolution TEM image of cerium oxide nanocrystals on the ReV. The cerium oxide nanocrystals are indicated by white curves, and the corresponding lattice spacing is labeled by white line. Representative pictures of dissected colon tissues and total colon length. Survival rates of mice in each group monitored for 24 h. Survival rate was detected from each of 8 mice ($n$ =8). Reprinted with permission from Zhao et al. [107] Copyright 2021, Elsevier.