Figure 6.

Representative ROS inducers and relative delivery applications for tumor therapy. (a) Representative photosensitizer of ROS inducers. (b) Formation of Fe₃O₄@P-NPO/PEG-Glc@Ce6 nanoprobes and photodynamic therapy in MGC-803 tumor-bearing mice. Reprinted with permission from Yin et al. [41] Copyright 2017, Nature Publishing Group. (c) Schematic illustration of UCNP-based nanoparticles loaded MC540 (PDT agents) on the basis of the PDT strategy. Reprinted with permission from Ding et al. [129] Copyright 2015, The Royal Society of Chemistry. (d) Schematic illustration of the covalent functionalization of CNDs and their targeted intracellular production of ROS. Reprinted with permission from Ji et al. [130] Copyright 2020, The Royal Society of Chemistry. (e) Schematic illustration of the preparation of multifunctional BPN/MnO₂/DOX nanostructures and the systemic delivery of BPN/MnO₂/DOX as a versatile theranostic platform for MRI-guided multifunctional therapy. Reprinted with permission from Wu et al. [49] Copyright 2019, Elsevier.