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Roles of the MA1 and MA2 point mutations in compensation for both the BH10-LD3 and BH10-LD4 deletion mutations through generation of BH10-LD3-MA2 (□), BH10-LD3-MA2-MP2 (◊), BH10-LD3-MA2-MNC (○), BH10-LD4-MA1 (▵), BH10-LD4-MA1-MP2 (⊞), and BH10-LD4-MA1-MNC (◊+). These clones were transfected into COS-7 cells, and the progeny viruses obtained were used to infect MT-2 cells. ⊕, BH10; ▿, control.
