Table 3.
All-cause deaths and hazard ratios (HRs) according to vaccination status in univariate and multivariate analyses.
| Covariate | 1 Dose | 2 Doses | 3/4 Doses | |||
|---|---|---|---|---|---|---|
| Univariate | Multivariate | Univariate | Multivariate | Univariate | Multivariate | |
| HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |||
| Groups | 0.88 (0.78–1.00) ‡ | 2.40 (2.00–2.88) ** | 1.23 (1.16–1.32) * | 1.98 (1.75–2.24) ** | 1.21 (1.14–1.29) * | 0.99 (0.90–1.09) |
| Hypertension | 12.59 (11.58–13.69) * | 1.49 (1.23–1.82) ** | 11.47 (10.76–12.23) * | / | 9.65 (9.09–10.24) * | 1.24 (1.11–1.39) ** |
| Diabetes | 8.07 (7.31–8.90) * | 2.00 (1.60–2.49) ** | 6.71 (6.23–7.23) * | 1.74 (1.38–2.20) ** | 5.90 (5.51–6.31) * | 1.68 (1.48–1.90) ** |
| CVD | 11.56 (10.63–12.57) * | 1.60 (1.31–1.96) ** | 10.88 (10.21–11.60) * | 1.78 (1.44–2.20) ** | 10.03 (9.45–10.63) * | 1.86 (1.65–2.09) ** |
| Kidney disease | 17.89 (16.08–19.90) * | 1.77 (1.35–2.34) ** | 16.83 (15.56–18.20) * | 2.44 (1.84–3.24) ** | 15.89 (14.78–17.08) * | 2.47 (2.11–2.89) ** |
| Cancer | 9.34 (8.51–10.25) * | / | 8.65 (8.07–9.27) * | / | 7.62 (7.15–8.12) * | / |
| Infection | 0.58 (0.53–0.63) * | / | 0.35 (0.32–0.38) * | / | 0.61 (0.58–0.66) * | / |
| Age | 1.11 (1.11–1.11) * | / | 1.11 (1.11–1.12) * | / | 1.12 (1.11–1.12) * | / |
| Sex | 0.87 (0.81–0.95) * | 1.50 (1.27–1.78) ** | 0.95 (0.89–1.01) | / | 0.98 (0.93–1.04) | 1.37 (1.24–1.51) ** |
| COPD | 7.11 (6.40–7.91) * | 2.01 (1.56–2.60) ** | 6.28 (5.79–6.82) * | 2.89 (2.18–3.84) ** | 5.96 (5.52–6.43) * | 1.85 (1.59–2.15) ** |
HRs = hazard ratios; CI = Confidence Interval; ‡ p-value = 0.044; * significance with p-value ≤ 0.001; ** significance with p-value < 0.0001. The HRs indicated with “/” are the covariate stratified in order to correct the assumptions of the Proportional Cox Mode.