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. 2024 Jul 17;60(7):1148. doi: 10.3390/medicina60071148

Figure 2.

Figure 2

Comparative Levels of Rat Lung Tissue (A) Endothelin-1 (ET-1), (B) Hypoxia-Inducible Factor-1 (HIF-1)-α, (C) Nuclear Factor-kappa B (NF-κB), (D) Tumor Necrosis Factor (TNF)-α, (E) Ferric Reducing Antioxidant Power (FRAP) and (F) Prooxidant-Antioxidant Balance (PAB)across Control (n = 6), 3 Days Pulmonary contusion (PC) Performed (PC3, n = 8), PC3 with 100 mg/kg Bosentan (PC-B3, n = 8), 7 Days PC Performed (PC7, n = 7), and PC7 with 100 mg/kg Bosentan (PC-B7, n = 8) groups. Significant differences are indicated as follows: “a” indicates a significant difference compared to the control group, “b” indicates a significant difference compared to the PC3 group, and “c” indicates a significant difference compared to the PC7 group. * Means p < 0.05, ** means p < 0.01, and *** means p < 0.001.