Table 2.
Cut-off values of hemodynamic parameters for diagnosis of CLI or reduced probability of wound healing reported in main guidelines.
| Hemodynamic Parameters for Diagnosis of CLI or Reduced Probability of Wound Healing | ||||
|---|---|---|---|---|
| AP | ABI | TP | TcPO2 | |
| Consensus EWG I [26] | ≤50 mmHg | |||
| Consensus EWG II [27] | ≤50 mmHg | ≤30 mmHg | ||
| Rutherford Classification [21] | <40 mmHg for class 4 |
<30 mmHg for class 4 |
||
| <60 mmHg for class 5 and 6 |
<40 mmHg for class 5 and 6 |
|||
| TASC I [28] | <50–70 mmHg | ≤30–50 mmHg | ≤30–50 mmHg | |
| TASC II [19] | <50 mmHg, if rest pain <70 mmHg, if wounds or gangrene |
<30 mmHg, if rest pain <50 mmHg, if wounds or gangrene |
≤30–50 mmHg | |
| WIfI classification [29] | 70–100 mmHg (grade 1 ischemia) |
0.60–0.79 (grade 1 ischemia) |
40–59 mmHg (grade 1 ischemia) |
40–59 mmHg (grade 1 ischemia) |
| 50–70 mmHg (grade 2 ischemia) |
0.40–0.59 (grade 2 ischemia) |
30–39 mmHg (grade 2 ischemia) |
30–39 mmHg (grade 2 ischemia) |
|
| <50 mmHg (grade 3 ischemia) |
<0.40 (grade 3 ischemia) |
<30 mmHg (grade 3 ischemia) |
<30 mmHg (grade 3 ischemia) |
|
| 2016 AHA/ACC PAD Guidelines [72] | <30 mmHg | <30 mmHg | ||
| 2017 ESC PAD Guidelines [15] | <50 mmHg | <0.40 | <30 mmHg | <30 mmHg |
| 2019 Global vascular guidelines on the management of CLTI [35] | <30 mmHg | <30 mmHg | ||
| 2019 ESVM PAD Guidelines [7] | <30 mmHg | <30 mmHg | ||
| 2023 IWGDF, ESVS, SVS PAD Guidelines in Diabetes Mellitus and a Foot Ulcer [17] | <50 mmHg | <0.40 | <30 mmHg | <30 mmHg |
| 2024 ESVS PAD Guidelines [18] | <30 mmHg | <30 mmHg | ||
| 2024 ACC/AHA PAD Guidelines [16] | <30 mmHg | <30 mmHg | ||