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. 2024 Jun 29;12(7):1330. doi: 10.3390/microorganisms12071330

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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BA.2 lineages’ evolution from 2022 to 2023. (a) Turnover of Omicron BA.2 lineages in Umbria. (b) Schematic representation of Spike glycoprotein structure and amino acid substitutions of prevalent BA.2 lineages. Abbreviations used: VOC, Variant of Concern; S1, Subunit 1; S2, Subunit 2; NTD, N-Terminal Domain; RBD, Receptor Binding Domain; SD1, Subdomain 1; SD2, Subdomain 2; FP, Fusion Peptide; HR1, Heptad Repeat 1; CH, Central Helix; CD, Connector Domain; HR2, Heptad Repeat 2; CT, Cytoplasmic Tail.