Fig. 5.

MERS-S specific cellular immune responses in mice with DNA-Prime/VTT-Boost strategy at different time points. A The scheme of DNA-Prime/VTT-Boost strategy. B MERS-S specific IFN-γ⁺ T cells were measured by ELISpot at 4-, 8-, and 11-weeks post-vaccination. C MERS-S specific CD8⁺ T cells were measured by ICS at 4-, 8-, and 11-weeks post-vaccination. Result analysis referenced Fig. 3B. D The percentages of MERS-S specific functional CD8⁺ T cells were detected by ICS. Result analysis referenced Fig. 3C. Bars represented the mean ​± ​SD.