Table 1.
Human radiation dose estimates calculated from data collected using Sprague Dawley rats (male and female) at four time points (10, 20, 60, and 120 min); see ESI for biodistribution data used in calculations.
| 18F-FluoFAPI | Gender-Averaged Dose |
|---|---|
| Target Organ | mSv/MBq |
| Adrenals | 7.11 × 10−3 |
| Brain | 2.03 × 10−3 |
| Breasts | 8.25 × 10−3 |
| Esophagus | 8.16 × 10−3 |
| Eyes | 4.07 × 10−3 |
| Gallbladder Wall | 1.09 × 10−2 |
| Left colon | 1.42 × 10−2 |
| Small Intestine | 1.96 × 10−2 |
| Stomach Wall | 9.89 × 10−3 |
| Right colon | 1.90 × 10−2 |
| Rectum | 2.62 × 10−2 |
| Heart Wall | 6.97 × 10−3 |
| Kidneys | 1.18 × 10−2 |
| Liver | 6.64 × 10−3 |
| Lungs | 5.82 × 10−3 |
| Ovaries | 1.86 × 10−2 |
| Pancreas | 8.19 × 10−3 |
| Prostate | 2.32 × 10−2 |
| Salivary Glands | 8.38 × 10−3 |
| Red Marrow | 9.49 × 10−3 |
| Osteogenic Cells | 8.66 × 10−3 |
| Spleen | 6.62 × 10−3 |
| Testes | 8.35 × 10−3 |
| Thymus | 8.98 × 10−3 |
| Thyroid | 8.62 × 10−3 |
| Urinary Bladder Wall | 2.27 × 10−1 |
| Uterus | 3.12 × 10−2 |
| Total Body | 1.10 × 10−2 |
| Effective Dose: | 1.85 × 10−2 (mSv/MBq) |