Supplementary Table 4.
Clinical characteristics of female congenital hypogonadotropic hypogonadism patients in inheritance and de novo groups
| Patient | Age at diagnosis (years) | Diagnosis | Comorbidities | BMI (kg m−2) | LH (IU/l) (baseline) | FSH (IU/l) (baseline) | Estradiol (pg/ml) (baseline) | Inheritance |
|---|---|---|---|---|---|---|---|---|
| Female 1 | 14 | KS | - | 16.9 | 0.65 | 2.40 | 22 | Yes |
| Female 2 | 13 | nCHH | Skeletal abnormalities | 17.3 | 0.20 | 1.54 | 15 | Yes |
| Female 3 | 15 | nCHH | - | 23.1 | 0.20 | 0.24 | 19 | No |
| Female 4 | 15 | nCHH | Short stature | 20.3 | 0.48 | 0.64 | 15 | No |
Comorbidities (-): no. KS: Kallmann syndrome; nCHH: normosmic congenital hypogonadotropic hypogonadism; BMI: body mass index; LH: luteinizing hormone; FSH: follicle-stimulating hormone