Table 3.
Positive selection pressure experienced by the HA gene of H5N8 subtype avian influenza viruses.
| H5N8 | Epitopes |
Other | ||||
|---|---|---|---|---|---|---|
| A | B | C | D | E | ||
| 2015–2017 | 139 | – | – | – | – | 30/99/492 |
| 2017–2019 | – | – | – | – | 88/113 | 191/565 |
| 2019–2022 | – | – | – | – | 88 | 538/548 |
Note: Positive selection pressure on the HA gene was assessed by dividing the data into three time segments. The epitope regions (A–D) were based on Yamashita's research and Dzimianski's research (Wiley et al., 1981; Yamashita et al., 2010), while other regions were grouped under the "other” category.