Table 2.
The visual appearance and % RSD of polymers with dispersion agents.
| Polymer | Dispersion Agent | % RSD | Visual Appearance |
|---|---|---|---|
| HPMC (5 cp) |
Polyethylene glycol 400 | 0.44 | Surface crack, Surface roughness |
| Polyoxyl 35 castor oil | 2.79 | Surface roughness, TD aggregation | |
| Polyethylene glycol 40 hydrogenated castor oil | 3.08 | TD aggregation | |
| Triethyl citrate | 2.84 | Non-homogenous layer | |
| Polyethylene oxide | 3.83 | Surface crack | |
| Polyvinylalcohol–Polyethylene glycol copolymer | 3.82 | Non-homogenous layer | |
| HPC-SL | Polyethylene glycol 400 | 0.43 | Very good |
| Polyoxyl 35 castor oil | 2.46 | TD aggregation, Surface crack | |
| Polyethylene glycol 40 hydrogenated castor oil | 2.52 | Surface crack | |
| Triethyl citrate | 3.11 | Non-homogenous layer | |
| Polyethylene oxide | 2.65 | Surface roughness | |
| Polyvinylalcohol–Polyethylene glycol copolymer | 2.72 | Non-homogenous layer | |
| Pullulan | Polyethylene glycol 400 | 0.31 | Surface roughness |
| Polyoxyl 35 castor oil | 2.68 | TD aggregation | |
| Polyethylene glycol 40 hydrogenated castor oil | 2.54 | Surface roughness | |
| Triethyl citrate | 3.02 | Non-homogenous layer | |
| Polyethylene oxide | 3.04 | TD aggregation, Surface roughness | |
| Polyvinylalcohol–Polyethylene glycol copolymer | 2.99 | Non-homogenous layer |
RSD: Relative standard deviation, TD: tadalafil.