Figure 2.

Circulating DENV-1 genotypes in 16 countries across three regions in Asia from the 1950s to 2023. DENV-1 envelope sequences were obtained from GenBank and categorized by genotype and year for each country. The number of DENV cases was aggregated for sequences collected prior to 1989 and for those collected between 1990 and 1999. Differently colored dots represent the genotypes indicated in the legend, with dot size corresponding to the number of sequences. *1 = Genome Detective classification; *2 = Goncalvez [42] and Chen and Vasilakis classification [34].