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. 2024 Jun 27;16(7):1036. doi: 10.3390/v16071036

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Multivariate ANOVA (MANOVA) reveals significant correlations between clinical markers of SIV and malaria infection, as well as neutrophil frequency and function and peripheral markers of GI dysfunction. Pearson’s partial correlation coefficients were generated using a MANOVA for 14 different parameters (VL; anemia; absolute CD4+ count; peripheral neutrophils; plasma zonulin; sCD4; I-FABP; LBP; NE; cathepsin G; CitH3; IP-10; MCP-1; and CRP). The correlation coefficients were adjusted against animal number. Boxes highlighted in light green represent positive correlations trending towards significance (0.05 < p < 0.07), and boxes highlighted in dark green or red represent statistically significant positive and negative correlations, respectively (p < 0.05).