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(A) Overall study design. Two female pigtail macaques (PTMs, NV18 & NV19) were inoculated with SIVmac239, followed by SARS-CoV-2 (WA1/2020) challenge approximately one year later. (B) Quantification of SIVmac239 RNA levels in plasma over time (quantitative RT PCR). CD4+ T-cell kinetics following SIVmac239 infection in blood (C), bronchoalveolar lavage (BAL) (D), and gut (E).
