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. 2024 Jun 21;73(8):1253–1266. doi: 10.1007/s00011-024-01892-7

Fig. 4.

Fig. 4

NLRP1 is associated with senescence in humans. A β-Gal and Ki-67 immunostaining in liver section from a patient with a NLRP1 gain of function mutation. B Venn Diagrams showing genes that are changed in both selected datasets (left), and genes that are upregulated (middle) or downregulated (right). GSEA analysis showing two gene datasets enrichered for inflammatory response and targets of senescences genes is shown below (color figure online)