Table 4.
Enriched Wiki-Pathway terms for upregulated DEGs in T2 group compared to T0 group.
| Enriched pathway Term (WikiPathway) | q-value | Combined score | Genes |
|---|---|---|---|
| Oxidative phosphorylation WP623 | 3.28E − 09 | 3310.898281 | ND6;ND1;ND3;ND2;ND5;ND4 |
| Electron Transport Chain (OXPHOS system in mitochondria) WP111 | 4.55E − 08 | 1583.835259 | ND6;ND1;ND3;ND2;ND5;ND4 |
| Mitochondrial complex I assembly model OXPHOS system WP4324 | 9.83E − 08 | 2233.049633 | ND6;ND1;ND2;ND5;ND4 |
| Senescence and Autophagy in Cancer WP615 | 0.002335 | 261.8466943 | SERPINB2;CXCL8;INHBA |
| Gastrin signaling pathway WP4659 | 0.002599 | 233.6510707 | SERPINB2;CXCL8;BIRC3 |
| Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway WP2203 | 0.009694 | 297.4766814 | CXCL8;IL7R |
| Hematopoietic Stem Cell Differentiation WP2849 | 0.011176 | 240.7359739 | CSF3;NFATC2 |
| Glucocorticoid Receptor Pathway WP2880 | 0.016611 | 173.5450943 | TNFAIP3;BIRC3 |
| TNF-alpha signaling pathway WP231 | 0.026347 | 119.1462592 | TNFAIP3;BIRC3 |
| Nuclear Receptors Meta-Pathway WP2882 | 0.026697 | 52.16380457 | SERPINB2;TNFAIP3;BIRC3 |
| Cytosine methylation WP3585 | 0.048188 | 549.1072571 | TET3 |
| Regulation of toll-like receptor signaling pathway WP1449 | 0.048188 | 66.53066798 | TNFAIP3 |