Table 5.
Enriched Wiki-Pathway terms for down-regulated DEGs in T2 group compared to T0 group.
| Enriched pathway term (WikiPathway) | q-value | Combined score | Genes |
|---|---|---|---|
| Adipogenesis WP236 | 0.006401258 | 290.6570558 | BMP3;EGR2;ID3 |
| TGF-beta Receptor Signaling WP560 | 0.020494571 | 355.7433228 | FOS;SMAD6 |
| TGF-beta receptor signaling in skeletal dysplasias WP4816 | 0.020494571 | 323.519069 | FOS;SMAD6 |
| Peptide GPCRs WP24 | 0.026577362 | 233.6130223 | OXTR;NPY2R |
| ESC Pluripotency Pathways WP3931 | 0.048946823 | 126.7131058 | FOS;SMAD6 |
| Regulation of toll-like receptor signaling pathway WP1449 | 0.048946823 | 98.52423894 | FOS;SMAD6 |
| Brain-derived neurotrophic factor (BDNF) signaling pathway WP2380 | 0.048946823 | 93.75610919 | EGR2;FOS |
| Myometrial relaxation and contraction pathways WP289 | 0.048946823 | 83.74321389 | OXTR;FOS |
| Iron metabolism in placenta WP2007 | 0.048946823 | 520.8353408 | SLC40A1 |
| Bone morphogenic protein (BMP) signaling and regulation WP1425 | 0.048946823 | 520.8353408 | SMAD6 |
| Neuroinflammation WP4919 | 0.048946823 | 469.1243344 | FOS |
| Transcriptional cascade regulating adipogenesis WP4211 | 0.048946823 | 469.1243344 | EGR2 |
| ncRNAs involved in STAT3 signaling in hepatocellular carcinoma WP4337 | 0.048946823 | 469.1243344 | SOX4 |
| H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity WP3969 | 0.048946823 | 425.939424 | SOX4 |
| ID signaling pathway WP53 | 0.048946823 | 358.0671609 | ID3 |
| MAPK pathway in congenital thyroid cancer WP4928 | 0.048946823 | 358.0671609 | FOS |