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. 2024 Jul 27;14:17246. doi: 10.1038/s41598-024-68348-0

Table 2.

GO analysis of DEGs in HCC samples.

Expression Category Term Pathway Count P-value
Downregulated GOTERM_BP GO:0,019,752 Carboxylic acid metabolic process 8 0.000119
GOTERM_BP GO:0,043,436 Oxoacid metabolic process 8 0.000123
GOTERM_BP GO:0,051,186 Cofactor metabolic process 6 0.00019
GOTERM_BP GO:0,006,082 Organic acid metabolic process 8 0.000213
GOTERM_BP GO:0,044,712 Single-organism catabolic process 7 0.000978
GOTERM_CC GO:0,072,562 Blood microparticle 4 0.002264
GOTERM_CC GO:0,005,615 Extracellular space 8 0.009116
GOTERM_CC GO:0,071,682 Endocytic vesicle lumen 2 0.028872
GOTERM_CC GO:0,034,364 High-density lipoprotein particle 2 0.043832
GOTERM_CC GO:1,990,777 Lipoprotein particle 2 0.06505
GOTERM_MF GO:0,005,343 Organic acid:sodium symporter activity 3 0.000522
GOTERM_MF GO:0,005,319 Lipid transporter activity 4 0.000668
GOTERM_MF GO:0,015,370 Solute:sodium symporter activity 3 0.002592
GOTERM_MF GO:0,043,178 Alcohol binding 3 0.005814
Upregulated GOTERM_BP GO:0,007,049 Cell cycle 27 5.46281E−14
GOTERM_BP GO:0,022,402 Cell cycle process 24 5.56823E−13
GOTERM_BP GO:0,000,280 Nuclear division 17 4.77487E−12
GOTERM_BP GO:0,000,278 Mitotic cell cycle 20 1.00515E−11
GOTERM_BP GO:0,048,285 Organelle fission 17 1.26476E−11
GOTERM_CC GO:0,005,694 Chromosome 19 8.00975E−10
GOTERM_CC GO:0,044,427 Chromosomal part 16 6.50626E−08
GOTERM_CC GO:0,005,819 Spindle 10 7.84562E−07
GOTERM_CC GO:0,098,687 Chromosomal region 10 2.354E−06
GOTERM_CC GO:0,000,775 Chromosome, centromeric region 8 3.51466E−06
GOTERM_MF GO:0,005,524 ATP binding 17 2.26573E−06
GOTERM_MF GO:0,016,462 Pyrophosphatase activity 13 2.70007E−06
GOTERM_MF GO:0,016,818 Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 13 2.76894E−06
GOTERM_MF GO:0,016,817 Hydrolase activity, acting on acid anhydrides 13 2.83937E−06
GOTERM_MF GO:0,032,559 Adenyl ribonucleotide binding 17 3.09998E−06

GO gene ontology, BP biological process, CC cell component, MF molecular function.