FIG. 2.
Predicted ORF organization of HHV-6 strain HST. Repeat regions (DRL, DRR, R1, R2, and R3) are boxed; telomeric repeat regions (T1 and T2) are denoted by striped bars; UR is indicated by a solid line. Protein coding regions are indicated as open arrows and are numbered DR1, DR2, DR3, DR6, DR7, DR8, DRHN1, and DRHN2 within the direct repeats and HN1, HN2, HN3, and U1 to U100 (excluding U78, U88, U92, U93, and U96) within the UR. The Ori is indicated by an asterisk. These regions are further described in Table 1 and in the text. The US22 gene family is shaded. Abbreviations not given in text: GCR, G-protein-coupled receptor; Ig, Ig immunoglobulin superfamily; RR, large subunit of ribonucleotide reductase; mCP, minor capsid protein; CA, capsid assembly protein; Teg, tegument protein; Pol, DNA polymerase; tp, transport protein; mDBP, major single-stranded DNA binding protein; TA, conserved herpesvirus transactivator; dUT, dUTPase; Pts, protease/assembly protein; pp65/71, phosphoprotein 65/71K; MCP, major capsid protein; PT, phosphotransferase; Exo, exonuclease; OBP, origin binding protein; Hel, helicase; UDG, uracil-DNA glycosylase; Che, chemokine; AAV rep1, adeno-associated virus replication protein homolog.