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. 2024 Jun 21;26(2):80–86. doi: 10.1016/j.ccrj.2024.03.001

Table 2.

Decision bounds and operating characteristics of the original group sequential adaptive plan.

Stage Infor-mation rate Bounds accept H0 Bounds reject H0 Signifi-cance level (one-sided) α spent Power achieved Sample size
1 0.5 2.963 0.0015 0.0015 0.1647 2x309
2 1.0 1.969 1.969 0.0245 0.0250 0.8010 2x309