Table 4.

Linear mixed effects regression with average change in pain score as outcome.

Variable	Estimate (95% confidence interval)	p-value
Intervention assignment
Control	Reference
Uno	1.247 (0.442–2.062)	0.004*
Duo	1.149 (0.344–1.965)	0.008*
Total uses during assignment	0.158 (−0.042–0.356)	0.122

^*Significant at p < 0.05.