TABLE 1.

Strand transfer activities of HIV-1 and SIV IN with HIV-1 and SIV oligonucleotide substrates^a

Recombinant IN	Activity
	HIV-1 U5	HIV-1 U3b	SIV U5b	SIV U3b
HIV-1 wt	1.00	0.20	0.85	0.75
SIV wt	1.00	0.25	0.97	0.92
SIV H12Ac	0.02	ND	ND	ND
SIV H16Ac	0.10	ND	ND	ND
N-terminal His SIVc	0.85	ND	ND	ND

^aOligonucleotides are described in Materials and Methods. For each substrate, INs were tested in duplicate at four different protein concentrations (25, 50, 100, and 200 nM). ND, not determined. 

^bActivity relative to HIV-1 U5 substrate. 

^cActivity relative to SIV wt enzyme.