FIG. 6.

Blocking of HSV infection with soluble HveC truncations. HSV-1 KOS tk12 was preincubated with variable concentrations of soluble HveC truncations or BSA prior to addition to M3A (A), IMR5 (B), or SY5Y (C) cells. Cells were lysed at 5.5 h postinfection, and the β-galactosidase activity was measured. A value of 100% of entry corresponds to the β-galactosidase activity induced after infection with HSV-1 KOS tk12 at a similar multiplicity of infection (0.5 to 1 PFU/cell) in the absence of soluble inhibitor.