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A) Representative immunohistochemical staining of Col-I, OCN, RANKL, iNOS, Arg-1, CD68, CD206 and VEGF in bone defect areas (scale bar: 100 μm). B) Semi-quantification of positively stained in A) (DM: diabetes mellitus, AB: autologous bone, MetS: Metformin scaffolds; n = 6 per group, data are provided as means ± SD, *p < 0.05, **p < 0.01).
