Table 1.

Meta-analytic Outcomes of Early Detection Strategies

Outcome	k Studies	n INT	n CTRL	Hedges’ g			Z Scores	P	Test for Heterogeneity			Egger’s Test
				Mean	95% CI				Q	I 2	P	T Values	P
Functioninga	8 (10)	1182	1010	0.281	0.073	0.488	2.653	.008	27.310	74.368	<.001	0.209	.841
Total psychopathologyb	7 (10)	1032	902	0.186	−0.173	0.546	1.016	.310	49.654	87.916	<.001	0.307	.771
Admission rates	3 (3)	348	406	0.179	−0.146	0.504	1.08	.280	5.747	65.202	.056	0.143	.908
Quality of life	4 (5)	546	456	0.154	−0.217	0.525	0.812	.417	13.193	77.261	.004	4.182	.053
Positive symptomsc	8 (14)	809	828	0.078	−0.126	0.283	0.749	.454	26.951	74.027	<.001	0.367	.726
Negative symptomsd	10 (16)	1231	1024	0.078	−0.064	0.219	1.078	.281	20.719	56.559	.014	0.638	.541
Employment rates	7 (7)	1307	1247	0.025	−0.124	0.173	0.324	.746	7.585	20.901	.270	0.262	.804
Depressive symptomse	3 (3)	328	282	0.003	−0.157	0.162	0.031	.975	0.059	0.000	.971	0.333	.795

Note: ^aFunctioning was evaluated with the Global Assessment of Functioning (GAF),⁹ the Social and Occupational Functioning Assessment Scale (SOFAS)¹⁰ or the Global Functioning: Role (GFR); Global Functioning: Social (GFS).^11,12

^bTotal psychopathology was evaluated with the Positive and Negative Syndrome Scale (PANSS)² or the Brief Psychiatric Rating Scale (BPRS).⁴

^cPositive symptoms were evaluated with the Positive and Negative Syndrome Scale (PANSS),² the Scale for the Assessment of Positive Symptoms (SAPS)³ or the Brief Psychiatric Rating Scale (BPRS).⁴

^dNegative symptoms were evaluated with the Positive and Negative Syndrome Scale (PANSS)² or the Scale for the Assessment of Negative Symptoms (SANS).⁵

^eDepressive symptoms were evaluated with the Hamilton Rating Scale for Depression (HAM-D),⁶ the Calgary Depression Scale for Schizophrenia (CDSS)⁷ or the Beck Depression Inventory (BDI).⁸

Bold values indicate P < 0.05.