Table 2.
Provider-reported toxicity—proton.
| Group |
|||||
|---|---|---|---|---|---|
| Covariate | Statistics | Level | Proton+RS N = 50 |
Proton-RS N = 26 |
P-valuea |
| A-GU | N (Col %) | 0 | 6 (12.24) | 1 (3.85) | .59 |
| N (Col %) | 1 | 10 (20.41) | 6 (23.08) | ||
| N (Col %) | 2+ | 33 (67.35) | 19 (73.08) | ||
| A-GI | N (Col %) | 0 | 46 (93.88) | 18 (69.23) | .01 |
| N (Col %) | 1 | 3 (6.12) | 6 (23.08) | ||
| N (Col %) | 2+ | 0 (0) | 2 (7.69) | ||
| L-GU | N (Col %) | 0 | 22 (46.81) | 6 (26.09) | .15 |
| N (Col %) | 1 | 4 (8.51) | 1 (4.35) | ||
| N (Col %) | 2+ | 21 (44.68) | 16 (69.57) | ||
| L-GI | N (Col %) | 0 | 43 (91.49) | 17 (73.91) | .08 |
| N (Col %) | 1 | 4 (8.51) | 5 (21.74) | ||
| N (Col %) | 2+ | 0 (0) | 1 (4.35) | ||
| R-GU | N (Col %) | 0 | 25 (53.19) | 6 (26.09) | .08 |
| N (Col %) | 1 | 2 (4.26) | 1 (4.35) | ||
| N (Col %) | 2+ | 20 (42.55) | 16 (69.57) | ||
| R-GI | N (Col %) | 0 | 45 (95.74) | 17 (73.91) | .01 |
| N (Col %) | 1 | 2 (4.26) | 5 (21.74) | ||
| N (Col %) | 2+ | 0 (0) | 1 (4.35) | ||
Notes: Univariable analysis of CTCAE v5.0 toxicity at specified time points in proton-treated patients.
Abbreviations: Proton+RS, proton with rectal spacer; Proton-RS, proton without rectal spacer; and A/L/R GU and GI, acute (<3 months), max late (≥3 months), most recent (≥3 months) genitourinary and gastrointestinal toxicities, respectively. P values <0.05 included in bold.
a
The P-value is calculated by χ2 test or Fisher exact, where appropriate.