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. 2024 Jul 27;15:6343. doi: 10.1038/s41467-024-50673-7

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 5 — a Schematics for APE1 constructs. b Immunoblot showing expression levels of exogenous APE1 constructs and depletion of endogenous APE1 and ALC1. Representative of three blots. c Sensitivities of the indicated SUM149PT cell lines to MMS (left) and olaparib (right). Data are presented as mean ± s.e.m from three biologically independent experiments. Source data are provided as a Source data file.