TABLE 3.

Frequency of enriched pathways.

Pathways	Frequency
Blood coagulation Platelet microparticle generation	8
Cell adhesion Plasmin signalling	7
Cytoskeleton remodelling Keratin filaments	6
Development Transcriptional regulation of megakaryopoiesis	6
Eosinophil granule protein release in asthma	6
Immune response CCR3 signalling in eosinophils	6
Immune response LPS‐induced platelet activation	6
Platelet activation during ADAM‐TS13‐deficient thrombotic microangiopathy development	6
SHH signalling in colorectal cancer	6
Th2 cytokine‐ and TNF‐alpha‐induced inflammatory response in asthmatic airway fibroblasts	6

Note: The first column shows pathways, and the second column shows the frequency that these pathways were differentially enriched between healthy and clusters 1:5 based on the transcriptomics and proteomics datasets.