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. 2024 Jun 28;17(6):1413–1422. doi: 10.14202/vetworld.2024.1413-1422

Table-2.

Antigenicity, allergenic, and solubility characteristics of selected S. aureus proteins.

S. aureus protein PDB ID Name of the protein Number of amino acids Stability index Predicted scaled solubility Total number of negative/positive amino acid Antigenicity Pairwise multiple sequence alignment

Score Possible cross-reaction with the host
1amx Collagen Binding domain of adhesin 1183 16.89 (stable) 0.579 – Soluble, pI: 7.380 (Asp+Glu): 180/(Arg+Lys): 166 The sequence is probable allergen −141 Non-host interacting
1yn3 Extracellular adherence protein 476 20.27 (stable) 0.905 Highly soluble, pI: 10.010 (Asp+Glu): 35/(Arg+Lys): 81 The sequence is probable allergen 10 Host interacting
1nu7 Staphylocoagulase thrombin complex Chain D 660 25.66 (stable) 0.487 – Soluble, pI: 9.660 (Asp+Glu): 89/(Arg+Lys): 93 The sequence is probable allergen −154 Non-host interacting
2b71 Teichoic acid 327 21.68 (stable) 0.527 – Soluble, pI: 9.750 (Asp+Glu): 38/(Arg+Lys): 54 The sequence is probable allergen −57 Non-host interacting
1edk Protein A domain B 508 51.46 (unstable) 0.894 – Soluble, pI: 4.530 (Asp+Glu): 79/(Arg+Lys): 71 The sequence is probable non-allergen 63 Host interacting
2gi9 Protein GB1 593 20.50 (stable) 0.899 – Soluble, pI: 4.390 (Asp+Glu): 100/(Arg+Lys): 74 The sequence is probable allergen 101 Host interacting
1n67 Clumping factor A precursor 933 49.93 (unstable) 0.702 – Soluble, pI: 4.850 (Asp+Glu): 211/(Arg+Lys): 48 The sequence is probable non-allergen −154 Non-host interacting
2noj Extracellular fibrinogen binding complex 109 13.31 (stable) 0.758 – Soluble, pI: 10.780 (Asp+Glu): 6/(Arg+Lys): 23 The sequence is probable non-allergen −206 Non-host interacting
1d20 Collagen binding protein Chain B 1183 16.89 (stable) 0.653 – Soluble, pI: 6.480 (Asp+Glu): 180/(Arg+Lys): 166 The sequence is probable allergen −367 Non-host interacting