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. 2024 Jun 21;17(6):1336–1347. doi: 10.14202/vetworld.2024.1336-1347

Table-3.

Prediction scores for 17 Veitchia merrillii fruit seed compounds which are associated with anthelmintic effects on Fasciola hepatica worms.

S. No. Compounds Anthelmintic Microtubule formation inhibitor Ca+2 channel activator Thioredoxin inhibitor Cholinergic antagonist Agonist apoptosis Ubiquinol- cytochrome- c reductase inhibitor TP53 expression enhancer Neurotransmitter antagonist Caspase 3 stimulant
Praziquantel (Control) 0.305 0 0.125 0 0.284 0 0 0 0.417 0
1 Gallic acid 0.356 0.234 0.612 0.409 0.573 0.562 0.915 0.718 0.64 0.413
2 Pyrogallol 0.524 0.23 0.69 0.864 0.641 0.775 0.914 0.744 0.66 0.507
3 Caffeic acid 0.277 0.285 0.521 0.563 0.482 0.711 0.843 0.776 0.523 0.579
4 Vanillic acid 0.253 0.309 0.363 0.488 0.57 0.512 0.922 0.713 0.556 0.64
5 Syringic acid 0.271 0.276 0.359 0.363 0.566 0.538 0.925 0.712 0.547 0.52
6 Rutin 0.321 0 0.292 0 0 0.747 0.512 0.893 0 0.893
7 Naringenin 0.213 0.237 0.476 0.578 0.462 0.709 0.868 0.822 0.642 0.557
8 Limonene 0.145 0.355 0.447 0.464 0.223 0.816 0.707 0.627 0.357 0.516
9 cis-β-ocimene 0.218 0.257 0.477 0.661 0.518 0.858 0.857 0.694 0.402 0.496
10 Allo-ocimene 0.289 0.302 0.518 0.706 0.232 0.948 0.958 0.785 0.456 0.382
11 Linalool oxide 0.43 0 0.341 0.429 0.195 0.67 0.782 0.52 0 0.713
12 Linalool 0.372 0.245 0.503 0.579 0.188 0.667 0.727 0.719 0.302 0.435
13 Methyl salicylate 0.561 0.15 0.341 0.429 0.233 0.425 0.67 0.52 0.572 0.713
14 Eucalyptol 0.314 0 0.22 0.603 0.174 0.221 0.735 0.58 0 0.296
15 Palmitate acid 0.23 0 0.246 0.769 0.641 0.342 0.907 0.74 0.642 0.355
16 Oleate acid 0.425 0.226 0.516 0.681 0.713 0.499 0.886 0.791 0.547 0.361
17 Linoleat acid 0.58 0.235 0.49 0.648 0.449 0.545 0.87 0.763 0.518 0.333
Average 0.340 0.197 0.438 0.543 0.393 0.620 0.823 0.709 0.422 0.512
Standard deviation 0.123 0.117 0.128 0.190 0.207 0.185 0.115 0.100 0.235 0.155

Score prediction ≥0.5 is marked in dark green Score prediction is between 0.3 and 0.5, it is marked in light green Score prediction ≤0.3 is marked in yellow