Table 5.
Outcomes of pregnancies in IVF and ICSI groups according to the cause of infertility
| Outcome | Female factor | Unexplained factor | |||||
|---|---|---|---|---|---|---|---|
| IVF | ICSI | p | IVF | ICSI | p | ||
| Among pregnancies with FHB | N | 17,893 | 4617 | 22,669 | 9743 | ||
| Fetal sacs with FHB | |||||||
| 1 | N (%) | 14,804 (82.7%) | 3800 (82.3%) | 0.84 | 19,085 (84.2%) | 8267 (84.9%) | 0.32 |
| 2 | N (%) | 3027 (16.9%) | 799 (17.3%) | 3494 (15.4%) | 1442 (14.8%) | ||
| 3–4 | N (%) | 62 (0.3%) | 18 (0.4%) | 90 (0.4%) | 34 (0.3%) | ||
| Miscarriage | N (%) | 2055 (11.5%) | 589 (12.8%) | 0.017 | 2832 (12.5%) | 1274 (13.1%) | 0.15 |
| Live births | N | 15,847 | 4030 | 19,847 | 8479 | ||
| Multiple live births | N (%) | 2509 (15.8%) | 674 (16.7%) | 0.33 | 2861 (14.4%) | 1189 (14.0%) | 0.76 |
| Among single live births starting with 1 FHB | N | 12,943 | 3266 | 16,440 | 7070 | ||
| Weeks of gestation | 0.45 | 0.39 | |||||
| < 32 | N (%) | 271 (2.1%) | 56 (1.7%) | 286 (1.7%) | 105 (1.7%) | ||
| 32–37 | N (%) | 2079 (16.1%) | 544 (16.7%) | 2368 (14.4%) | 1048 (14.8%) | ||
| ≥ 38 | N (%) | 10,502 (81.1%) | 2642 (80.9%) | 13,675 (83.2%) | 5875 (83.1%) | ||
| Missing data | N (%) | 91 (0.7%) | 24 (0.7%) | 111 (0.7%) | 42 (0.6%) | ||
| Birth weight (g) | 0.22 | 0.037 | |||||
| < 1500 | N (%) | 218 (1.7%) | 46 (1.4%) | 193 (1.2%) | 72 (1.0%) | ||
| 1500–2499 | N (%) | 804 (6.2%) | 204 (6.2%) | 980 (6.0%) | 386 (5.5%) | ||
| 2500–3999 | N (%) | 8844 (68.3%) | 2196 (67.2%) | 11,079 (67.4%) | 4756 (67.3%) | ||
| ≥ 4000 | N (%) | 797 (6.2%) | 192 (5.9%) | 1052 (6.4%) | 413 (5.8%) | ||
| Missing data | N (%) | 2280 (17.6%) | 628 (19.2%) | 3136 (19.1%) | 1433 (20.4%) | ||
FHB = Fetal Heartbeat, including cases of embryo splitting; IVF = conventional in vitro insemination; ICSI = intracytoplasmic sperm injection; 95%CI: 95% confidence interval