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. 2024 Jul 29;47(1):366. doi: 10.1007/s10143-024-02592-w

Table 1.

List of examined clinical parameters and their definitions [1, 79, 1113, 15, 17, 20, 27]

Parameter category Parameters/Definitions
Epidemiological data Age (defined as age at surgery)
Gender (defined as biological gender)
Medical history Hypertension (defined as documented diagnosis or intake of antihypertensive medication)
Diabetes mellitus (defined as documented diagnosis of type 1 or 2 diabetes or intake of oral antidiabetics or insulin)
Hyperlipidemia (defined as documented diagnosis or intakt of medication lowering the lipid or cholesterol levels in the blood)
Peripheral arterial disease (defined as documented diagnosis or imaging finding)
Heart disease (defined as documented diagnosis of myocardial infarction, coronary artery disease, cardia arrhytmia or other heart diseases)
Ischaemic stroke (defined as documented diagnosis or imaging finding at admission)
Thrombosis (defined as documented diagnosis)
Malignant tumor disease (defined as documented diagnosis regardless of affected organ)
Autoimmune disease (defined as documented diagnosis with need of immunosuppressive therapy)
Obesity (defined as a documented body mass index of > 30 kg/m2)
Nicotine abuse (defined as ex-nicotine abuse or continued nicotine abuse)
Alcohol abuse (defined ot consumption of > 50 g of alcohol per week)
Contraceptive use and intake of hormone replacement products (at time of diagnosis, extracted from medical records or medication plans)
CT-imaging parameters Type of bleeding, shifting of the midline, intraventricular hemorrhage, hydrocephalus and ischaemia (all assed in the first CT-scan after SAH)
Aneurysm-related parameters Rupturestatus (defined by assessment of intraoperative findings, imaging findings and bleeding patterns in CT)
Multiplicity (defined as > / = 2 intracranial aneurysms)
Aneurysm localization (defined by assessment of angiography)
Clinical scores Glasgow coma scale at admission and discharge (defined by neurological examination at admission and discharge)
Modified rankin scale at discharge (defined by neurological examination at discharge)
Hunt and Hess grade, WFNS score and Fisher grade at admission (defined by neurological examination at admission and imaging findings)
Treatment-related parameters Previous and current treatment and treatment-modality (extracted from medical records)
Surgery-related parameters Number of clips used (extracted from the operation report)
Type of craniotomy (extracted from the operation report)
Occurence of intraoperative rupture (extracted from the operation report)
Need for and duration of intraoperative temporary clipping (extracted from the operation report)
Use of intraoperative indocyanine green angiography and/or microvascular doppler sonography (extracted from the operation report)
Need for primary or secondary decompressive hemicraniectomy (extracted from the operation report)
Occurence and type of postoperative stroke or haemorrhage (extracted from the postoperative CT-scans)
Degree of occlusion of the aneurysm and need for revision in partially/unoccluded aneurysms (extracted from the postoperative angiography and medical records)
Complication-related parameters Hydrocephalus, placement of an external ventricular drainage or ventriculoperitoneal shunt (extracted from medical records)
Vasospasm, method of vasospasm-detection and treatment via endovascular spasmolysis (extracted from medical records)
Follow-up data Time of follow-up, perfusion of the aneurysm and modified rankin scale at follow-up (extracted from medical records)