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Requirement of ICP0 for cell cycle arrest
| Virus | IE expression of:
|
G2/M cell cycle arresta | ||||
|---|---|---|---|---|---|---|
| ICP4 | ICP27 | ICP22 | ICP47 | ICP0 | ||
| d92 | − | − | + | + | + | Yes |
| d95 | − | − | − | + | + | Yes |
| d97 | − | − | + | + | − | No |
| d99 | + | + | + | + | − | No |
| d100 | − | + | + | + | − | No |
| d103 | − | + | − | − | + | Yes |
| d106 | − | − | − | − | + | Yes |
| d109 | − | − | − | − | − | No |
Cell cycle arrest was defined by flow cytometry of propidium iodide-stained infected cells at 24 h postinfection.
