Table 1.
Baseline characteristics
| Variable | Whole cohort N = 372 |
No calcimimetic n = 262 | Cinacalcet n = 75 | Etelcalcetide n = 35 | P-value |
|---|---|---|---|---|---|
| Age, yr, median (IQR) | 53 (42–62) | 54 (43–63) | 52 (42–59) | 49 (40–65) | 0.62 |
| Female gender no. (%) | 127 (34) | 91 (35) | 19 (25) | 17 (49) | 0.05 |
| Kidney disease no. (%) | 0.85 | ||||
| Diabetes | 58 (16) | 41 (16) | 11 (15) | 6 (17) | |
| Glomerular disease | 96 (26) | 68 (26) | 22 (29) | 6 (17) | |
| Interstitial nephritis | 39 (10) | 29 (11) | 8 (11) | 2 (6) | |
| Hypertension/renal vascular disease | 20 (5) | 14 (5) | 3 (4) | 3 (9) | |
| Inherited | 83 (22) | 55 (21) | 19 (25) | 9 (26) | |
| Other | 26 (7) | 20 (8) | 2 (3) | 4 (11) | |
| Unknown | 50 (13) | 35 (13) | 10 (13) | 5 (14) | |
| Dialysis vintage, mo, median (IQR) | 39 (20–62) | 33 (17–52) | 57 (35–71) | 69 (35–84) | <0.001 |
| Treatment at the time of KT | |||||
| Ca-containing phosphate binder no. (%) | 231 (62) | 168 (64) | 42 (56) | 21 (60) | 0.40 |
| Non-Ca containing phosphate binder no. (%) | 177 (48) | 109 (42) | 47 (63) | 21 (60) | 0.002 |
| Vitamin D no. (%) | 238 (64) | 167 (64) | 48 (64) | 23 (66) | 0.98 |
| Active vitamin D no. (%) | 123 (33) | 77 (30) | 35 (47) | 11 (31) | 0.02 |
| Type of donor no. (%)a | 0.02 | ||||
| Deceased | 311 (84) | 210 (80) | 69 (92) | 32 (91) | |
| Living | 61 (16) | 52 (20) | 6 (8) | 3 (9) |
Ca, calcium; IQR, interquartile range; KT, kidney transplantation; iPTH, intact parathormone.
a
More data are available in Supplementary Table S2.