Table 3.
Outcomes after transplantation
| Outcome | Whole cohort N = 372 |
No calcimimetic n = 262 | Cinacalcet n = 75 | Etelcalcetide n = 35 | P-value |
|---|---|---|---|---|---|
| Follow-up after transplantation, d, median (IQR) | 1064 (367–1658) | 1078 (377–1652) | 1464 (728–1980) | 349 (241–646) | <0.001 |
| Parathyroidectomy after transplantation, no. (%) | 21 (6) | 2 (1) | 9 (12) | 10 (29) | <0.001 |
| Time to parathyroidectomy after transplantation, d, median (IQR) | 347 (90–503) | 612 (503–721) | 480 (364–819) | 80 (42–292) | <0.001 |
| Delayed graft function, no. (%) | 52 (14) | 29 (11) | 15 (21) | 8 (23) | 0.04 |
| Delayed graft functiona, no. (%) | 51/309 (17) | 28/210 (13) | 15/67 (22) | 8/32 (25) | 0.09 |
| Loss of kidney allograft, no. (%) | 15 (4) | 12 (5) | 3 (4) | 0 (0) | 0.43 |
| Death no. (%) | 37 (10) | 28 (11) | 7 (9) | 2 (6) | 0.64 |
| Max. calcium level, mMmol/l, median (IQR) | 2.58 (2.51–2.67) | 2.56 (2.49–2.62) | 2.63 (2.58–2.75) | 2.81 (2.60–2.99) | <0.001 |
| Time to max. calcium level, d, median (IQR) | 102 (48–201) | 111 (49–187) | 112 (61–229) | 52 (29–157) | 0.02 |
| eGFR at 12 mo, ml/min per 1.73 m2, median (IQR) | 56 (45–71) | 56 (45–70) | 54 (43–71) | 66 (53–85) | 0.05 |
eGFR, estimated glomerular filtration rate; IQR, interquartile range; max., maximal; no.; number.
a
In patients with a deceased donor kidney transplantation.