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. 2024 Jun 24;5(3):100321. doi: 10.1016/j.xhgg.2024.100321

Table 3.

Multivariate linear regression of the practical utility subscale assessed at baseline, post-results disclosure, and 6m post-results disclosure

Baseline (n = 913)
Post-results disclosure (n = 927)
6m Post-results disclosure (n = 831)
β (95% CI) p value β (95% CI) p value β (95% CI) p value
Socioeconomic factors
Education level
 HS/GED/post-HS training vs. <HS 1.83 (0.06, 3.61) 0.042 1.29 (−1.08, 3.65) 0.286 0.95 (−1.71, 3.61) 0.485
 College graduate vs. <HS −0.42 (−2.56, 1.72) 0.702 −3.24 (−6.10, −0.38) 0.027 −1.20 (−4.46, 2.05) 0.469
 College+ vs. <HS −1.73 (−4.07, 0.60) 0.145 −4.09 (−7.22, −0.97) <0.001 −3.62 (−7.17, −0.06) 0.046
Survey language
 Spanish vs. English −0.03 (−1.74, 1.67) 0.971 0.78 (−1.47, 3.03) 0.497 0.95 (−1.57, 3.47) 0.458
Insurance type
 Private vs. Public −1.47 (−2.88, −0.05) 0.042 −1.66 (−3.56, 0.24) 0.086 −2.30 (−4.48, −0.12) 0.039
Healthcare distrust
 Values subscale 0.07 (−0.15, 0.28) 0.538 0.13 (−0.16, 0.41) 0.382 −0.14 (−0.46, 0.18) 0.397
 Competence subscale −0.49 (−0.76, −0.21) 0.001 −0.46 (−0.83, −0.10) 0.014 −0.43 (−0.84, −0.01) 0.044
Health Literacy Score −0.14 (−0.33, 0.05) 0.161 −0.28 (−0.54, −0.03) 0.028 −0.20 (−0.49, 0.09) 0.176
Clinical factors
Case-level clinical interpretation
 Positive/likely positive vs. negative 8.33 (5.95, 10.71) <0.001 5.27 (2.57, 7.96) <0.001
 Uncertain vs. negative −0.34 (−2.13, 1.45) 0.708 −2.35 (−4.40, −0.30) 0.025
 Positive/likely positive vs. uncertaina 8.67 (6.95, 10.89) <0.001 7.62 (5.12, 10.12) <0.001
Previous genetic testing
 Yes vs. no −1.21 (−2.44, 0.01) 0.052 −1.69 (−3.34, −0.04) 0.044 −2.11 (−3.98, −0.24) 0.027

HS, high school; GED, General Education Development Test.

Bold enteries signify significant results.

a

Post-hoc analyses were conducted using uncertain result as the reference variable for case-level clinical interpretation.