Table 3.
Multivariate linear regression of the practical utility subscale assessed at baseline, post-results disclosure, and 6m post-results disclosure
Baseline (n = 913) |
Post-results disclosure (n = 927) |
6m Post-results disclosure (n = 831) |
||||
---|---|---|---|---|---|---|
β (95% CI) | p value | β (95% CI) | p value | β (95% CI) | p value | |
Socioeconomic factors | ||||||
Education level | ||||||
HS/GED/post-HS training vs. <HS | 1.83 (0.06, 3.61) | 0.042 | 1.29 (−1.08, 3.65) | 0.286 | 0.95 (−1.71, 3.61) | 0.485 |
College graduate vs. <HS | −0.42 (−2.56, 1.72) | 0.702 | −3.24 (−6.10, −0.38) | 0.027 | −1.20 (−4.46, 2.05) | 0.469 |
College+ vs. <HS | −1.73 (−4.07, 0.60) | 0.145 | −4.09 (−7.22, −0.97) | <0.001 | −3.62 (−7.17, −0.06) | 0.046 |
Survey language | ||||||
Spanish vs. English | −0.03 (−1.74, 1.67) | 0.971 | 0.78 (−1.47, 3.03) | 0.497 | 0.95 (−1.57, 3.47) | 0.458 |
Insurance type | ||||||
Private vs. Public | −1.47 (−2.88, −0.05) | 0.042 | −1.66 (−3.56, 0.24) | 0.086 | −2.30 (−4.48, −0.12) | 0.039 |
Healthcare distrust | ||||||
Values subscale | 0.07 (−0.15, 0.28) | 0.538 | 0.13 (−0.16, 0.41) | 0.382 | −0.14 (−0.46, 0.18) | 0.397 |
Competence subscale | −0.49 (−0.76, −0.21) | 0.001 | −0.46 (−0.83, −0.10) | 0.014 | −0.43 (−0.84, −0.01) | 0.044 |
Health Literacy Score | −0.14 (−0.33, 0.05) | 0.161 | −0.28 (−0.54, −0.03) | 0.028 | −0.20 (−0.49, 0.09) | 0.176 |
Clinical factors | ||||||
Case-level clinical interpretation | ||||||
Positive/likely positive vs. negative | – | 8.33 (5.95, 10.71) | <0.001 | 5.27 (2.57, 7.96) | <0.001 | |
Uncertain vs. negative | – | −0.34 (−2.13, 1.45) | 0.708 | −2.35 (−4.40, −0.30) | 0.025 | |
Positive/likely positive vs. uncertaina | – | 8.67 (6.95, 10.89) | <0.001 | 7.62 (5.12, 10.12) | <0.001 | |
Previous genetic testing | ||||||
Yes vs. no | −1.21 (−2.44, 0.01) | 0.052 | −1.69 (−3.34, −0.04) | 0.044 | −2.11 (−3.98, −0.24) | 0.027 |
HS, high school; GED, General Education Development Test.
Bold enteries signify significant results.
Post-hoc analyses were conducted using uncertain result as the reference variable for case-level clinical interpretation.