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. 2024 Jun 24;5(3):100321. doi: 10.1016/j.xhgg.2024.100321

Table 4.

Multivariate linear regression of the educational utility subscale assessed at baseline, post-results disclosure, and 6m-post results disclosure

Baseline (n = 908)
Post-results disclosure (n = 924)
6m Post-results disclosure (n = 828)
β (95% CI) p value β (95% CI) p value β (95% CI) p value
Socioeconomic factors
Education level
 HS/GED/post-HS training vs. <HS 1.08 (0.18, 1.97) 0.018 1.18 (0.10, 2.27) 0.032 1.60 (0.25, 2.94) 0.020
 College graduate vs. <HS 0.43 (−0.64, 1.51) 0.430 0.23 (−1.08, 1.54) 0.726 0.85 (−0.80, 2.49) 0.311
 College+ vs. <HS 0.18 (−1.00, 1.35) 0.769 0.39 (−1.05, 1.82) 0.598 0.16 (−1.64, 1.96) 0.862
Survey language
 Spanish vs. English 0.19 (−0.68, 1.06) 0.663 0.25 (−0.78, 1.28) 0.631 1.17 (−0.10, 2.45) 0.071
Insurance type
 Private vs. public −0.28 (−0.99, 0.44) 0.447 −0.49 (−1.36, 0.38) 0.267 0.22 (−0.88, 1.32) 0.695
Healthcare distrust
 Values subscale 0.04 (−0.07, 0.14) 0.508 0.05 (−0.08, 0.19) 0.418 −0.01 (−0.17, 0.16) 0.965
 Competence subscale −0.15 (−0.29, −0.02) 0.029 −0.09 (−0.26, 0.08) 0.303 −0.14 (−0.35, 0.08) 0.206
 Health Literacy Score −0.01 (−0.11, 0.08) 0.779 −0.11 (−0.22, 0.01) 0.070 0.03 (−0.12, 0.17) 0.722
Clinical factors
Case-level clinical interpretation
 Positive/likely positive vs. negative 3.02 (1.93, 4.11) <0.001 0.62 (−0.74, 1.98) 0.372
 Uncertain vs. negative −0.59 (−1.41, 0.23) 0.159 −1.19 (−2.23, −0.16) 0.024
 Positive/likely positive vs. uncertaina 3.61 (2.59, 4.62) <0.001 1.81 (0.55, 3.07) 0.005
Previous genetic testing
 Yes vs. no −0.01 (−0.62, 0.61) 0.982 0.12 (−0.63, 0.87) 0.757 −0.30 (−1.24, 0.65) 0.539

HS, high school; GED, General Education Development Test.

Bold enteries signify significant results.

a

Post-hoc analyses were conducted using uncertain result as the reference variable for case-level clinical interpretation.