Table 1.
Clinical characteristics of individuals undergoing bariatric surgery.
N | pre-surgery | N | post-surgery | delta post-pre | P post vs pre | |
---|---|---|---|---|---|---|
Sex (female/male) | 6/3 | |||||
Age (years) | 9 | 52.2 [25.9; 63.9] | 9 | 55.5 [27.5; 65.5] | 1.6 [0.8; 6.7] | |
BMI (kg/m2) | 9 | 54.0 [43.0; 71.7] | 9 | 39.8 [30.9; 44.7] | −15.2 [−37.5; −9.4] | 3.9 x 10−3 |
bodyfat (%) | 9 | 49.1 [35.5; 64.1] | 8 | 41.2 [10.0; 63.3] | −6.5 [−25.5; 8.6] | 0.08 |
CRP (μg/mL) | 9 | 10.0 [3.1; 18.1] | 9 | 0.9 [0.6; 9.9] | −3.9 [−13.8;-2.1] | 0.004 |
HbA1c (%) | 9 | 5.6 [4.7; 7.9] | 8 | 5.5 [5.0; 7.3] | −0.6 [−0.7; 1.1] | 0.20 |
FPG (mmol/L) | 9 | 5.9 [5.4; 7.8] | 9 | 5.3 [4.5; 8.4] | −0.2 [−2.3; 1.9] | 0.57 |
FPI (pmol/L) | 9 | 201.1 [97.8; 487.8] | 7 | 117.5 [24.9; 378.9] | −49.8 [−188.7; 177.8] | 0.69 |
HOMA-IR | 9 | 7.0 [3.3; 20.7] | 6 | 3.2 [0.8; 15.8] | −0.9 [−6.2; 7.8] | 1 |
Triglycerides mmol/L) | 9 | 1.6 [1.1; 3.5] | 6 | 1.1 [0.6; 2.0] | −0.3 [−1.3; 0.7] | 0.22 |
Cholesterol (mmol/L) | 9 | 4.7 [3.4; 5.5] | 6 | 3.9 [3.5; 5.2] | −0.6 [−1.0; 0.2] | 0.06 |
LDL-cholesterol (mmol/L) | 9 | 3.1 [2.1; 3.8] | 6 | 2.6 [1.8; 3.4] | −0.4 [−1.7; 0.03] | 0.06 |
HDL-cholesterol (mmol/L) | 9 | 0.9 [0.7; 1.2] | 6 | 1.2 [1.0; 1.5] | 0.3 [0.05; 0.6] | 0.03 |
ALAT (μkat/L) | 9 | 0.7 [0.3; 2.0] | 9 | 0.3 [0.2; 1.4] | −0.2 [−1.8; 0.5] | 0.07 |
ASAT (μkat/L) | 9 | 0.5 [0.4; 1.0] | 9 | 0.4 [0.3; 0.9] | −0.1 [−0.7; 0.4] | 0.30 |
gGT (μkat/L) | 9 | 0.7 [0.3; 0.8] | 9 | 0.3 [0.1; 2.3] | −0.2 [−0.5; 1.4] | 0.13 |
Values are shown as median [min; max] P: significance levels based on Wilcoxon signed rank test. Significant P (<0.05) are marked bold. ALAT: alanine aminotransferase; ASAT: aspartate aminotransferase; BMI: body mass index; CRP: C reactive protein; FPG: fasting plasma glucose; FPI: fasting plasma insulin; gGT: gamma-glutamyl transferase; HbA1c: glycated haemoglobin A1c; HDL: high density lipoprotein; HOMA-IR: homeostatic model assessment for insulin resistance; LDL: low density lipoprotein.