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. 2024 Jul 11;67(14):11841–11867. doi: 10.1021/acs.jmedchem.4c00465

Figure 6.

Figure 6

Live cell confocal imaging of HEK293TR cells. (A) Induced CB1R-HEK293TR cells incubated with 29 (250 nM, yellow). White arrow: Intracellular staining by 29. (B) Induced CB2R-HEK293TR cells incubated with 29 (250 nM, yellow). (C) Uninduced CB1R-HEK293TR cells incubated with 29 (250 nM, yellow). (D) Induced CB1R-HEK293TR cells preincubated with competitor 6 (5 μM, 30 min) and then 29 (250 nM, yellow). Images recorded after 10 min at 63× magnification with nucleus counter stain Hoechst 33342 (blue). Scale bars 20 μm images are representative of two to three independent experiments.