Table 3.

Change in HbA1c, blood glucose, body weight and composition from day 0 to day 45 and day 90.

	Change from day 0 to day 45			Change from day 0 to day 90
	DSF (n = 112)	Control (n = 118)	p-value	DSF (n = 111)	Control (n = 118)	p-value
HbA1c (%)	−0.44 ± 0.06	−0.26 ± 0.06	0.015	−0.50 ± 0.07	−0.21 ± 0.07	0.002
Blood glucose (mmol/L)	0.16 ± 0.17	0.28 ± 0.17	0.593	−0.14 ± 0.17	0.32 ± 0.17	0.036
Body weight (kg)	−1.30 ± 0.14	−0.61 ± 0.14	<0.001	−1.74 ± 0.19	−0.76 ± 0.18	<0.001
Body weight (%)	−1.72 ± 0.19	−0.82 ± 0.18	<0.001	−2.27 ± 0.25	−1.05 ± 0.24	<0.001
Fat mass (kg)	−1.13 ± 0.18	−0.72 ± 0.18	0.070	−1.77 ± 0.20	−0.96 ± 0.19	0.001
Fat mass (%)	−0.82 ± 0.23	−0.63 ± 0.23	0.509	−1.44 ± 0.26	−0.79 ± 0.26	0.047
Fat-free mass (kg)	−0.16 ± 0.19	−0.02 ± 0.18	0.547	0.0001 ± 0.20	−0.05 ± 0.20	0.845
Fat-free mass (%)	0.82 ± 0.23	0.63 ± 0.23	0.507	1.44 ± 0.26	0.79 ± 0.26	0.047
Visceral adipose tissue (L)	−0.16 ± 0.03	−0.08 ± 0.03	0.039	−0.23 ± 0.03	−0.07 ± 0.03	<0.001
Visceral adipose tissue (%)	−4.46 ± 1.27	−1.65 ± 1.22	0.080	−6.52 ± 1.28	−0.95 ± 1.22	<0.001

Analysis of covariance (ANCOVA), adjusting for treatment group, site, randomization strata HbA1c level and BMI, and baseline value for the specific outcome variable. Values are LSM ± SE. Statistically significant findings (p < 0.05) are in bold. For some variables, sample sizes are smaller than the overall stated sample sizes. HbA1c, glycated hemoglobin; LSM, least square mean; SE, standard error.