Ho 2009.
Methods | Randomised study performed at the IVF centre of China Medical University Hospital in Taiwan | |
Participants | A total of 44 women were enrolled in the study: 30 were randomised to acupuncture group and 14 to the control (no‐acupuncture group). The two groups were described as comparable for demographics including age and cause of infertility |
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Interventions | The study compared electro‐acupuncture (twice a week for two weeks, from cycle day 2 to the day prior to oocyte retrieval) with no acupuncture around the time of oocyte retrieval | |
Outcomes | Outcome measures studied were clinical pregnancy and the pulsatility index (PI) of left and right uterine arteries | |
Assisted conception protocols | Protocol breakdown not provided | |
Notes | The study was designed to assess the impact of acupuncture on uterine artery blood flow and clinical pregnancy rate | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not stated |
Allocation concealment (selection bias) | Unclear risk | ‘randomly assigned to one of the two groups by selection of a sealed envelope.’ |
Blinding (performance bias and detection bias) All outcomes | High risk | Control group received no treatment |
Incomplete outcome data (attrition bias) All outcomes | High risk | 30 randomised to acupuncture group, and 26 to control group (but 12 in the control group dropped out), leaving 30 in the acupuncture group and only 14 in the control group. |
Selective reporting (reporting bias) | Unclear risk | No LBR outcome data reported. |
Other bias | Low risk | None known |